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1

Design, synthesis and biological activity of new neurohypophyseal hormones analogues conformationally restricted in theN-terminal part of the molecule. Highly potent OT receptor antagonists

Kwiatkowska, Anna, Ptach, Monika, Borovičková, Lenka, Slaninová, Jiřina, Lammek, Bernard, Prahl, Adam

Journal:

Year:

2012

Language:

english

File:

PDF, 348 KB

english, 2012

2

Potent V2/V1a vasopressin antagonists with C-terminal ethylenediamine-linked retro-amino acids

Manning, Maurice, Przybylski, Jozef, Grzonka, Zbigniew, Nawrocka, Eleonora, Lammek, Bernard, Misicka, Aleksandra, Cheng, Ling Ling, Chan, W. Y., Wo, Nga Ching, Sawyer, Wilbur H.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.34 MB

english, 1992

3

Highly Potent 1-Aminocyclohexane-1-Carboxylic Acid Substituted V 2 Agonists of Arginine Vasopressin

Kowalczyk, Wioleta, Prahl, Adam, Derdowska, Izabela, Dawidowska, Olga, Slaninová, Jiřina, Lammek, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

4

Effects of bradykinin and prostaglandin inhibition on systemic and regional hemodynamics in conscious normotensive rats

Wang, Yi-Xin, Gavras, Irene, Lammek, Bernard, Bresnahan, Margaret, Gavras, Haralambos

Journal:

Journal of Hypertension

Year:

1991

File:

PDF, 675 KB

1991

5

The Effects of N-Terminal Part Modification of Arginine Vasopressin Analogues with 2-Aminoindane-2-carboxylic Acid: A Highly Potent V 2 Agonist

Kowalczyk, Wioleta, Sobolewski, Dariusz, Prahl, Adam, Derdowska, Izabela, Borovičková, Lenka, Slaninová, Jiřina, Lammek, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 42 KB

english, 2007

6

Biologically active analogues of arginine vasopressin containing conformationally restricted dipeptide fragments

BERNARD LAMMEK, MAŁGORZATA CZAJA, IZABELA DERDOWSKA, ELŻBIETA ŁEMPICKA, PIOTR SIKORA, WITOLD SZKRÓBKA, HENRYK I. TRZECIAK

Journal:

Chemical Biology & Drug Design

Year:

1998

Language:

english

File:

PDF, 536 KB

english, 1998

7

Structure–activity relationships of novel peptide agonists of the human bradykinin B2 receptor

Simon Bélanger, Veronica Bovenzi, Jérome Côté, Witold Neugebauer, Muriel Amblard, Jean Martinez, Bernard Lammek, Martin Savard, Fernand Gobeil Jr.

Journal:

Year:

2009

Language:

english

File:

PDF, 946 KB

english, 2009

8

The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells

Levesque, Christine, Fugère, Martin, Kwiatkowska, Anna, Couture, Frédéric, Desjardins, Roxane, Routhier, Sophie, Moussette, Philippe, Prahl, Adam, Lammek, Bernard, Appel, Jon R., Houghten, Richard A.,

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.47 MB

english, 2012

9

Synthesis and some pharmacological properties of oxytocin and vasopressin analogs with sarcosine or N-methyl-L-alanine in position 7

Grzonka, Zbigniew, Lammek, Bernard, Kasprzykowski, Franciszek, Gazis, Diana, Schwartz, Irving L.

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 747 KB

english, 1983

10

Influence of Conformationally Constrained Amino Acids Replacing Positions 2 and 3 of Arginine Vasopressin (AVP) and Its Analogues on Their Pharmacological Properties

Sobolewski, Dariusz, Prahl, Adam, Derdowska, Izabela, Kwiatkowska, Anna, Slaninova, Jirina, Lammek, Bernard

Journal:

Protein & Peptide Letters

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

11

Synthesis and some pharmacological properties of 18 potent O-alkyltyrosine-substituted antagonists of the vasopressor responses to arginine-vasopressin

Manning, Maurice, Lammek, Bernard, Bankowski, Krzysztof, Seto, Janny, Sawyer, W. H.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 1015 KB

english, 1985

12

Synthesis and some pharmacological properties of potent and selective antagonists of the vasopressor (V1-receptor) response to arginine-vasopressin

Manning, Maurice, Stoev, Stoytcho, Bankowski, Krzysztof, Misicka, Aleksandra, Lammek, Bernard, Wo, Nga Ching, Sawyer, Wilbur H.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

13

ChemInform Abstract: RESOLUTION OF RACEMIC 3-HYDROXYPENTADECANOIC ACID INTO ITS ENANTIOMERS AND DETERMINATION OF THEIR ABSOLUTE CONFIGURATION

LAMMEK, BERNARD, NEUGEBAUER, WITOLD, KUPRYSZEWSKI, GOTFRYD

Journal:

Chemischer Informationsdienst

Year:

1976

File:

PDF, 102 KB

1976

14

Investigation of cis/trans ratios of peptide bonds in AVP analogues containing N-methylphenylalanine enantiomers

Emilia Sikorska, Magdalena J. Ślusarz, Rafał Ślusarz, Wioleta Kowalczyk, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

15

Study of the Interactions between Neurophysin II and Dipeptide Ligand by Means of Molecular Dynamics

Rajmund Kazmierkiewicz, Cezary Czaplewski, Bernard Lammek, Jerzy Ciarkowski, Bogdan Lesyng

Journal:

Journal of Molecular Modeling

Year:

1995

Language:

english

File:

PDF, 1.19 MB

english, 1995

16

Design, Synthesis and Structure-Activity Relationship of New Arginine Vasopressin Analogues Containing Proline Derivatives in Position 2

Kwiatkowska, Anna, Lewandowska, Monika, Borovičková, Lenka, Slaninová, Jiřina, Lammek, Bernard, Prahl, Adam

Journal:

Chemical Biology & Drug Design

Year:

2013

Language:

english

File:

PDF, 802 KB

english, 2013

17

Novel analogues of arginine vasopressin containing α-2-indanylglycine enantiomers in position 2

Anna Kwiatkowska, Małgorzta Śleszyńska, Izabela Derdowska, Adam Prahl, Dariusz Sobolewski, Lenka Borovičková, Jiřina Slaninová, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2010

Language:

english

File:

PDF, 125 KB

english, 2010

18

Molecular Modeling of Meta II Rhodopsin

Rafał Ślusarz, Magdalena J. Ślusarz, Bernard Lammek, Jerzy Ciarkowski

Journal:

Molecular Informatics

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

19

Synthetic antagonists of in vivo antidiuretic and vasopressor responses to arginine-vasopressin

Manning, Maurice, Lammek, Bernard, Kolodziejczyk, Alexander M., Seto, J., Sawyer, W. H.

Journal:

Journal of Medicinal Chemistry

Year:

1981

Language:

english

File:

PDF, 950 KB

english, 1981

20

Analogs of arginine vasopressin modified in the N-terminal part of the molecule with a conformationally constrained cis-peptide bond motif

Dariusz Sobolewski, Adam Prahl, Izabela Derdowska, Jiřina Slaninová, Krzysztof Kaczmarek, Janusz Zabrocki, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2007

Language:

english

File:

PDF, 124 KB

english, 2007

21

125I-d(CH2)5[Tyr(Me)2,Tyr(NH2)9]AVP: Iodination and binding characteristics of a vasopressin receptor ligand

Jack Elands, Claude Barberis, Serge Jard, Bernard Lammek, Maurice Manning, Wilbur H. Sawyer, E.Ronald de Kloet

Journal:

Year:

1988

Language:

english

File:

PDF, 431 KB

english, 1988

22

Analogues of Neurohypophyseal Hormones, Oxytocin and Arginine Vasopressin, Conformationally Restricted in the N-Terminal Part of the Molecule

Kowalczyk, Wioleta, Prahl, Adam, Derdowska, Izabela, Sobolewski, Dariusz, Olejnik, Jadwiga, Zabrocki, Janusz, Borovicková, Lenka, Slaninová, Jiřina, Lammek, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

23

Synthesis and some pharmacological properties of [4-threonine,7-sarcosine]oxytocin, a peptide with high oxytocic potency, and of [4-threonine,7-N-methylalanine]oxytocin

Grzonka, Zbigniew, Lammek, Bernard, Gazis, Diana, Schwartz, Irving L.

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 316 KB

english, 1983

24

ChemInform Abstract: ANWENDUNG DER AKTIVEN 2,4,6-TRICHLOR-PHENYL- UND P-N-ACETYL-SULFAMOYLPHENYL-ESTER VON N-BENZYLOXYCARBONYL-AMINOSAEUREN BEI DER SYNTH. DES C-TERMINALEN TETRAPEPTIDS VON GASTRIN UND SEINEM ANALOGEN

DABROWSKA, MALGORZATA, KUPRYSZEWSKI, GOTFRYD, LAMMEK, BERNARD, MUZALESKI, FELIKS

Journal:

Chemischer Informationsdienst

Year:

1972

File:

PDF, 121 KB

1972

25

Synthesis and Some Pharmacological Properties of Six New Analogs of Arginine-Vasopressin Substituted in Position 2 with β-Thienylalanine or Prolonged on the N-Terminus with 1-Adamantaneacetic Acid

Konieczna, Ewa, Czaja, Malgorzata, Lammek, Bernard, Slaninová, Jiřina, Barth, Tomislav

Journal:

Collection of Czechoslovak Chemical Communications

Year:

1993

File:

PDF, 462 KB

1993

26

Analogues of arginine vasopressin modified in position 2 and 3 with conformationally constrained dipeptide fragments

Elżbieta Łempicka, Izabela Derdowska, Wioleta Kowalczyk, Olga Dawidowska, Adam Prahl, Marcin Janecki, Tomasz Jasiński, Henryk I. Trzeciak, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2005

Language:

english

File:

PDF, 103 KB

english, 2005

27

Analogues of AVP modified in the N-terminal part of the molecule with Pip isomers: TFA-catalysed peptide bond hydrolysis

Dariusz Sobolewski, Adam Prahl, Anna Kwiatkowska, Jiřina Slaninová, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

28

New bradykinin analogs in contraction of rat uterus,☆

Henryk I Trzeciak, Wojciech Kozik, Samed Melhem, Aleksandra Kania, Dariusz Dobrowolski, Adam Prahl, Izabela Derdowska, Bernard Lammek

Journal:

Year:

2000

Language:

english

File:

PDF, 162 KB

english, 2000

29

New acylated bradykinin analogues: effect on rat blood pressure and rat uterus

Dr Olga Dawidowska, Adam Prahl, Tomasz Wierzba, Łukasz Nowakowski, Wioleta Kowalczyk, Jiřina Slaninová, Bernard Lammek

Journal:

Journal of Peptide Science

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

30

Conformational studies of vasopressin analogues modified with N-methylphenylalanine enantiomers in dimethyl sulfoxide solution

Emilia Sikorska, Magdalena J. Ślusarz, Bernard Lammek

Journal:

Year:

2006

Language:

english

File:

PDF, 462 KB

english, 2006

31

Theoretical predictions of the impact of the trisubstituted pyrophosphate internucleotide bond on B DNA fragments

Bogusław Śmiech, Rajmund Kaźmierkiewicz, Janusz Bujnicki, Bernard Lammek

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

2005

Language:

english

File:

PDF, 449 KB

english, 2005

32

Design, Synthesis, and Structure–Activity Relationship Studies of a Potent PACE4 Inhibitor

Kwiatkowska, Anna, Couture, Frédéric, Levesque, Christine, Ly, Kévin, Desjardins, Roxane, Beauchemin, Sophie, Prahl, Adam, Lammek, Bernard, Neugebauer, Witold, Dory, Yves L., Day, Robert

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.33 MB

english, 2014

33

Synthesis and Biological Activity of Four Vasopressin Analogs Modified in Position 3 with β-Thienylalanine

Slaninová, Jiřina, Czaja, Malgorzata, Lammek, Bernard

Journal:

Collection of Czechoslovak Chemical Communications

Year:

1995

Language:

english

File:

PDF, 41 KB

english, 1995

34

Molecular Modelling of the Neurophysin II/Vasopressin Complex

Rajmund Kaźmierkiewicz, Cezary Czaplewski, Bernard Lammek, Jerzy Ciarkowski

Journal:

Molecular Informatics

Year:

1997

Language:

english

File:

PDF, 743 KB

english, 1997

35

A new highly potent antagonist of bradykinin

Bernard Lammek, Yi-Xin Wang, Irene Gavras, Haralambos Gavras

Journal:

Year:

1990

Language:

english

File:

PDF, 241 KB

english, 1990

36

Potentiometric and spectroscopic studies of the Cu(II) complexes of Ala-Arg8-vasopressin and oxytocin: Two vasopressin-like peptides

Wojciech Bal, Henryk Kozlowski, Bernard Lammek, Krzystof Rolka, Leslie D. Pettit

Journal:

Journal of Inorganic Biochemistry

Year:

1992

Language:

english

File:

PDF, 733 KB

english, 1992

37

Theoretical conformational analysis of three vasopressin antagonists with a modified cyclohexyl ring in the first thioacid residue

RAJMUND KAŹMIERKIEWICZ, ADAM LIWO, BERNARD LAMMEK

Journal:

Chemical Biology & Drug Design

Year:

1995

Language:

english

File:

PDF, 802 KB

english, 1995

38

Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue

Edyta Podstawka, Emilia Sikorska, Leonard M. Proniewicz, Bernard Lammek

Journal:

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

39

Novel analogues of bradykinin conformationally restricted in the C-terminal part of the molecule

Małgorzata Śleszyńska, Tomasz H. Wierzba, Krzysztof Malinowski, Lenka Borovičková, Izabela Małuch, Dariusz Sobolewski, Bernard Lammek, Jiřina Slaninová, Adam Prahl

Journal:

Journal of Peptide Science

Year:

2011

Language:

english

File:

PDF, 138 KB

english, 2011

40

Molecular Modeling of Interaction of the Vasopressin Analogs with Vasopressin and Oxytocin Receptors

Rafał Ślusarz, Magdalena J. Ślusarz, Rajmund Kaźmierkiewicz, Bernard Lammek

Journal:

Molecular Informatics

Year:

2003

Language:

english

File:

PDF, 888 KB

english, 2003

41

Novel Bradykinin Analogues Modified in the N-Terminal Part of the Molecule with a Variety of Acyl Substituents

Małgorzata Śleszyńska, Tomasz H. Wierzba, Krzysztof Malinowski, Tereza Tůmová, Bernard Lammek, Jiřina Slaninová, Adam Prahl

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2012

Language:

english

File:

PDF, 233 KB

english, 2012

42

The unusual co-ordination ability of vasopressin-like peptides; potentiometric and spectroscopic studies of some copper(II) and nickel(II) complexes

Kozlowski, Henryk, Radomska, Barbara, Kupryszewski, Gotfryd, Lammek, Bernard, Livera, Cynara, Pettit, Leslie D., Pyburn, Simon

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1989

Language:

english

File:

PDF, 628 KB

english, 1989

43

A Simple Method of Preparation of t -Butoxycarbonyl Amino Acids

GRZONKA, Zbigniew, LAMMEK, Bernard

Journal:

Year:

1974

File:

PDF, 66 KB

1974

44

Influence of enantiomers of 1-naphthylalanine in position 2 of VAVP and dVAVP on their pharmacological properties

Izabela Derdowska, Adam Prahl, Wioleta Kowalczyk, Marcin Janecki, Samed Melhem, Henryk I. Trzeciak, Bernard Lammek

Journal:

European Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 170 KB

english, 2005

45

Surprising Pharmacological Activity of Analogues Designed by Substitution of Position 3 in Arginine Vasopressin (AVP) and 8-D-Arginine Vasopressin with l-2-Naphthylalanine

BERNARD LAMMEK, EWA KONIECZNA, HENRYK I. TRZECIAK, ARTUR KOZLOWSKI, JACEK SZYMKOWIAK, RAFAL STOJKO, GOTFRYD KUPRYSZEWSKI

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 461 KB

english, 1996

46

Synthesis of arginine-vasopressins, modified in positions 1 and 2, as antagonists of the vasopressor response to the parent hormone

Lammek, Bernard, Rekowski, Piotr, Kupryszewski, Gotfryd, Melin, Per, Ragnarsson, Ulf

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 568 KB

english, 1988

47

2-O-Alkyltyrosine derivatives of 1-deaminoarginine-vasopressin: highly specific and potent antidiuretic agonists

Lammek, Bernard, Bankowski, Kryzsztof, Misicka, Aleksandra, Manning, Maurice, Seto, J., Sawyer, W. H.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 558 KB

english, 1989

48

Design of potent and selective antagonists of the vasopressor responses to arginine-vasopressin

Manning, Maurice, Lammek, Bernard, Kruszynski, Marian, Seto, Janny, Sawyer, Wilbur H.

Journal:

Journal of Medicinal Chemistry

Year:

1982

Language:

english

File:

PDF, 1.08 MB

english, 1982

49

Unusual gain in the coordination ability of vasopressin-like peptides towards Cu2+ ions by insertion of the highly hydrophobic side chain

Chruścinska, Elżbieta, Derdowska, Izabela, Kozłowski, Henryk, Lammek, Bernard, Łuczkowski, Marek, Ołdziej, Stanislaw, Świątek-Kozłowska, Jolanta

Journal:

New Journal of Chemistry

Year:

2003

Language:

english

File:

PDF, 478 KB

english, 2003

50

Theoretical Modeling of PrkCc, Serine–Threonine Protein Kinase Intracellular Domain, Complexed with ATP Derivatives

Paweł Gruszczyński, Rajmund Kaźmierkiewicz, Michał Obuchowski, Bernard Lammek

Journal:

Molecular Informatics

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

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